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Targets Recommended: COX

258

抑制剂 & 化合物

110

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295

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Cat. No. Product Name Target Signaling Pathways
T10032 COX-2-IN-2

COX Immunology/Inflammation; Neuroscience
COX-2-IN-2 是选择性的,诱导型的 COX2 抑制剂,IC50 值为0.24 μM。COX-2-IN-2 是具有抗炎和止痛活性的抗炎物。
T10033 COX-2-IN-1

COX Immunology/Inflammation; Neuroscience
COX-2-IN-1 是 一个强效的 COX-2 抑制剂,其 IC50 值为 3.9 μM。
T77618 COX-2-IN-34

COX Immunology/Inflammation; Neuroscience
COX-2-IN-34 是一种选择性的、口服有效的 COX-2 抑制剂,在小鼠实验过程中显示出抗炎活性且无胃溃疡毒性。
T62061 COX-2-IN-6

COX; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
COX-2-IN-6 是一种具有有效性、选择性且可口服的环氧化酶-2 (COX-2) 抑制剂,对 COX-2 具有抑制作用,IC50 为 0.84 μM,Ki 为 69 nM。COX-2-IN-6 对 COX-2 驱动的 PGE2 合成具有抑制作用,IC50 为 0.60 μM。COX-2-IN-6 可用于预防结直肠癌。
T7207 FK 3311

N-[4-乙酰基-2-(2,4-二氟苯氧基)苯基]-甲烷磺酰胺,FK-3311,COX-2 Inhibitor V

COX Immunology/Inflammation; Neuroscience
FK 3311 (COX-2 Inhibitor V) 是一种细胞渗透性和口服磺胺类药物,可作为 COX-2 抑制剂和非甾体抗炎药。
T0432 Diclofenac diethylamine

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Diclofenac diethylamine 是非选择性抗炎剂,通过活化 caspase 级联反应来诱导神经干细胞凋亡。它是一种COX 抑制剂,在 CHO 细胞中,对人COX-1和COX-2的IC50值分别为 4 和 1.3 nM。它对绵羊COX-1和COX-2的IC50值分别为 5.1 μM 和0.84 μM。
T0458 Indomethacin

Indocin,Indometacine,吲哚美辛,Indomethacine,Indometacin

Phospholipase; COX; PDE; Autophagy Autophagy; Immunology/Inflammation; Metabolism; Neuroscience
Indomethacin (Indometacin) 是一种可透过血脑屏障的,非选择性的COX1和COX2抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50值分别为 18 nM 和 26 nM。它通过干扰溶酶体的正常功能来破坏自噬流,是一种非甾体抗炎药。
T6737 Zaltoprofen

CN100,扎托布洛芬,Soleton

COX Immunology/Inflammation; Neuroscience
Zaltoprofen (Soleton) 是一种非甾体类抗炎剂,具有强大的抗炎作用和对炎性疼痛的止痛作用。它是可口服的COX-2抑制剂,对COX-1和COX-2的IC50值分别为 1.3 和 0.34 μM。
T0448 (S)-(+)-Ibuprofen

左旋布洛芬,Dexibuprofen,(S)-Ibuprofen,(S)-(+)-布洛芬

BCL; Thrombin; Cysteine Protease; COX; PPAR Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome
(S)-(+)-Ibuprofen (Dexibuprofen) 是 Ibuprofen 的 S(+)-对映异构体,能够有效的抑制COX-1(IC50:2.1 μM)和COX-2(IC50:1.6 μM),。它具有抗癌、退热、止痛,抗炎的效果。
T6470 Diclofenac Potassium

双氯芬酸钾,CGP-45840B,Cataflam,Voltfast

Apoptosis; Others; COX Apoptosis; Immunology/Inflammation; Neuroscience; Others
Diclofenac Potassium (CGP-45840B) 是一种非甾体抗炎药,用于减轻炎症并在某些情况下作为镇痛剂减轻疼痛。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。它是一种COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的IC50值分别为 5.1 μM 和0.84 μM。
T8356 FPL 62064

Lipoxygenase; COX Immunology/Inflammation; Metabolism; Neuroscience
FPL 62064 是 5-脂氧合酶和COX 双重抑制剂,具有抗炎活性,对 RBL-1 胞质 5-脂氧合酶和前列腺素合成酶 (环氧化酶) 的IC50值分别为 3.5 和 3.1 μM。
T1555 Diclofenac sodium

GP 45840,双氯芬酸钠

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Diclofenac sodium (GP 45840) 是一种非选择性抗炎剂,是 COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的 IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的 IC50值分别为 5.1 μM,0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。
T0196 Diclofenac

双氯芬酸,奥尔芬,Diclofenacum,Voltaren

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Diclofenac (Diclofenacum) 是一种具有抗炎活性的非甾体苯乙酸衍生物,是 COX 抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的 IC50值分别为 4 和 1.3 nM。它对绵羊 COX-1 和 COX-2 的 IC50值分别为 5.1 μM,0.84 μM。它通过活化 caspase 级联反应来诱导神经干细胞凋亡。
T22368 Metyrosine

甲酪氨酸,α-Methyltyrosine

COX Immunology/Inflammation; Neuroscience
Metyrosine (α-Methyltyrosine) 是一种选择性酪氨酸羟化酶抑制剂,可显著抑制高 COX-2 活性和有效控制血压,具有抗炎和抗溃疡作用。
T7838 Losartan Carboxaldehyde

COX Immunology/Inflammation; Neuroscience
Losartan Carboxaldehyde 是氯沙坦的中间醛代谢产物。它不能阻断 AT1-R ,但可以抑制内皮环氧合酶 (COX)-2 的表达,起到抗炎作用。
T7596 Firocoxib

非罗考昔,ML 1785713

COX Immunology/Inflammation; Neuroscience
Firocoxib (ML 1785713) 是一种可口服的 COX-2选择性抑制剂,IC50为 0.13 μM。它具有抗炎作用,对 COX-2的选择性比对 COX-1 的选择性高 58 倍,IC50为 7.5 μM。
T1562 Rebamipide

Proamipide,OPC12759,瑞巴派特

Free radical scavengers; COX; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience; oxidation-reduction
Rebamipide (OPC12759) 是一种粘膜保护剂,可诱导COX-2表达,增加PGE2水平,并以 COX-2 依赖性方式增强胃粘膜防御。
T23333 SC-58125

SC 58125,1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑

COX Immunology/Inflammation; Neuroscience
SC-58125 是一种选择性的环氧合酶2 (COX-2)的抑制剂,IC50值为 0.04 μM。它在体内外均表现出抗肿瘤活性,还可抑制炎症部位的水肿并具有缓解疼痛作用。
T3214 NS-398

N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide,NS398

COX Immunology/Inflammation; Neuroscience
NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) 是一种非甾体类抗炎剂,具有解热作用,可用于缓解疼痛的研究。它选择性抑制 COX-2的活性,IC50值为 3.8 μM。
T50005 Sertaconazole

Antifungal Microbiology/Virology
Sertaconazole 是一种广谱抗真菌药。
T2577 Dienogest

地诺孕素,STS 557

Apoptosis; Estrogen/progestogen Receptor; Progesterone Receptor; Autophagy Apoptosis; Autophagy; Endocrinology/Hormones; Others
Dienogest (STS 557) 是一种孕酮受体激动剂,作用于子宫内膜异位,有口服的子宫内膜活性。
T4646 TA-02

p38 MAPK; Autophagy Autophagy; MAPK
TA02 是一种Adezmapimod 类似物,是p38 MAPK 的抑制剂,其IC50值为 20 nM。它和Adezmapimod、SB 202190 具有相似的心源活性,可抑制 TGFBR-2
T78705 COX-2-IN-30

COX Immunology/Inflammation; Neuroscience
COX-2-IN-30 是苯磺酰胺衍生的口服活性 COX/5-LOX 双重抑制剂,其 IC50 值为 COX 同源物为 49 nM、5-LOX 同源物为 10.4 μM。此化合物还能纳摩尔级别 Ki 值抑制 hCA IX 与 hCA XII 亚型。COX-2-IN-30 具备镇痛、抗炎、致溃疡作用,不引发急性胃部反应。
T63480 COX-2-IN-26

COX-2-IN-26 是有效的、口服具有活力的、选择性的 COX-2 抑制剂,能够作用于 COX-1 (IC50: 10.61 μM)、COX-2 (IC50: 0.067 μM)、15-LOX (IC50: 1.96 μM)。COX-2-IN-26 具有抗炎作用,具有胃肠道安全性。
T63646 COX-2-IN-9

COX-2-IN-9 是选择性的、有效的、口服具有活力的 COX-2 抑制剂 (IC50: 10.17 μM)。COX-2-IN-9 的 COX-2 选择性比 Celecoxib 高。COX-2-IN-9 表现出良好的体内抗炎活性和低致溃疡效果。
T78706 COX-2-IN-31

COX Immunology/Inflammation; Neuroscience
COX-2-IN-31(化合物7b)是一种COX/5-LOX双重抑制剂,口服活性显著,对COX-2的IC50为60 nM,对5-LOX的IC50为0.9 μM。此外,COX-2-IN-31对跨膜蛋白hCA IX和hCA XII具有抑制作用,其Ki值分别为48.9 nM和5.8 nM,显示出镇痛和抗炎的生物活性。
T60457 COX-2-IN-11

COX-2-IN-11 (compound 7b2) 是COX-2的有效的选择性抑制剂。COX-2-IN-11 在炎症性疾病的研究方面具有潜力。
T61760 COX-2-IN-18

COX-2-IN-18 (Compound 3) is a highly effective COX-2 inhibitor with strong inhibitory activity against COX-2 (IC 50 = 0.775 μM). Its potency is comparable to the reference drug Celecoxib (IC 50 = 0.153 μM). This compound, COX-2-IN-18, shows promise in the field of cancer research [1].
T60978 COX-2-IN-7

COX-2-IN-7 (compound 4a) 是口服有效的COX-2 选择性抑制剂,其选择性高于 Celecoxib,IC50值为6.585 uM。COX-2-IN-7 在体内具有良好的抗炎和低致溃疡活性。
T79130 COX-2-IN-32

NF-κB NF-κB
COX-2-IN-32(Compound 2f)为一种抑制iNOS和COX-2的化合物,能够降低NF-κB表达,并抑制LPS诱导的RAW264.7巨噬细胞中NO产生,显示出抗炎活性(IC50: 11.2 μM)。
T79760 COX-2-IN-35

COX Immunology/Inflammation; Neuroscience
COX-2-IN-35(化合物7),作为选择性COX-2抑制剂,表现出4.37 nM的IC50,并展现抗炎活性。
T63348 COX-2-IN-23

COX-2-IN-23 是 COX-2 的选择性抑制剂,它对 COX-2COX-1 的IC50值分别为 0.28 和 20.14 μM。COX-2-IN-23 表现出抗炎作用以及低致溃疡效果。
T62175 COX-2-IN-8

COX-2-IN-8 (compound 6a) 是一种有效的、选择性的、口服具有活力的 COX-2 抑制剂 (IC50: 6.585 μM)。COX-2-IN-8 的 COX-2 选择性比 Celecoxib 高。COX-2-IN-8 在体内表现出良好的抗炎活性和低致溃疡效果。
T61264 COX-2-IN-19

COX-2-IN-19 (Compound 24) is a highly potent inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 1.76 μM. Notably, COX-2-IN-19 exhibits robust in vivo anti-inflammatory activity [1].
T22790 FR 122047

4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride,1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride,FR 122047盐酸盐

COX Immunology/Inflammation; Neuroscience
FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) 是一种口服有活性的、选择性的 COX-1 抑制剂(IC50:28 nM)。它在体内具有镇痛、抗炎、抗血小板的功能。
T61821 COX-2-IN-16

COX-2-IN-16 (compound 2b)为一种口服活性高、选择性强的COX-2抑制剂,其IC50为102 μM,能有效抑制NO产生并具备抗炎活性。
T61714 COX-2-IN-13

COX-2-IN-13 (compound 13e) is a highly potent and selective inhibitor of COX-2, demonstrating a remarkable IC50 value of 0.98 μM. It exhibits strong anti-inflammatory activity and has shown favorable results in vivo acute toxicity studies [1].
T63215 COX-2-IN-22

COX-2-IN-22 是一种能够透过血脑屏障的 COX-2 抑制剂 (IC50: 8.6 μM),也对AChE (IC50: 2.8 μM)、BChE (IC50: 6.3 μM)、β-Secretase (IC50: 15.3 μM)、LOX-5 (IC50: 13.9 μM) 和 DPPH (IC50: 6.8 μM)表现出抑制作用。
T16328 Nitroaspirin

2-乙酰氧基苯甲酸-3-硝酸甲基苯酯,NCX 4016

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Nitroaspirin (NCX 4016) 是一氧化氮供体和阿司匹林的硝基衍生物,与 Aspirin 结合可抑制环氧合酶=,可作为 COX-1 的直接和不可逆抑制剂。 它通过下调 EGFR/PI3K/STAT3 信号传导和调节 Bcl-2 家族蛋白,显着诱导顺铂耐药人卵巢癌细胞的细胞周期停滞和凋亡,具有抗血栓和抗血小板特性。
T64109 COX-2-IN-28

COX-2-IN-28 是一种有效的、选择性的 COX-2 抑制剂,能够作用于 COX-2 (IC50: 0.054 μM)、15-LOX (IC50: 2.14 μM)、COX-1 (IC50: 13.21 μM)。
T63943 COX-2-IN-10

COX-2-IN-10 是 COX-2 的有效抑制剂。COX-2-IN-10 对 IL-6、TNF-α 和 IL-1β 的产生表现出抑制作用。COX-2-IN-10 能够浓度依赖性地抑制 PGE2 的产生,其 IC50 值为 2.54 μM。COX-2-IN-10 在 mRNA 和蛋白水平上抑制 iNOS 和 COX-2 的表达。
T61711 COX-2-IN-14

COX-2-IN-14 (compound 2a) is a highly potent and selective inhibitor of COX-2 (cyclooxygenase-2), with strong binding affinity at the active site of COX-2 co-crystal. Demonstrating remarkable in vivo anti-inflammatory activity, COX-2-IN-14 effectively reduces ear edema and myeloperoxidase (MPO) activity in mice [1].
T60566 COX-2-IN-12

COX-2-IN-12 (compound 3b) 是一种有效的选择性COX-2抑制剂,IC50值为 19.98 μM。COX-2-IN-12 是一种抗炎剂,并且在体内急性毒性研究中显示出安全性。
T64063 COX-2-IN-24

COX-2-IN-24是一种口服具有活力的 COX-2 抑制剂 (IC50: 0.17 μM),具有抗炎和低致溃疡作用。
T60464 COX-2-IN-20

COX-2-IN-20 (Compound 5d) 是一种选择性口服活性的COX-2抑制剂(IC 50 = 17.9 nM),具有抗炎活性。
T62259 COX-2-IN-21

COX-2-IN-21 (Compound 5c) 一种口服具有活力的、选择性的 COX-2 抑制剂 (IC50: 0.039 μM)。COX-2-IN-21 具有良好的抗炎潜力。
T63336 COX-2-IN-29

COX-2-IN-29 是口服具有活力的 COX-2 的选择性抑制剂 (IC50: 0.005 μM)。
T62142 COX-2-IN-17

COX-2-IN-17 是一种有效的、具有血脑屏障通透性的 COX-2(环氧化酶 -2) 抑制剂 (IC50: 0.02 μM),具有抗炎和镇痛活性。
T78754 COX-2-IN-33

COX Immunology/Inflammation; Neuroscience
COX-2-IN-33(化合物5f)作为一种COX-2抑制剂(IC50=45.5 nM),同样具备潜在抗炎作用。该化合物能抑制促炎细胞因子的生成,同时确保胃部安全。
T23046 N-tert-butyl-α-Phenylnitrone

(Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮

ROS; COX Immunology/Inflammation; Neuroscience
N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) 是基于硝酮的自由基清除剂,可形成一氧化氮自旋加合物。它可以穿透血脑屏障,抑制 COX2的催化活性,有 ROS 清除、抗炎、神经保护、抗衰老和抗糖尿病的作用。

化合物

COX-2-IN-2
Cat.No: T10032
Synonym:
Target: COX
COX-2-IN-1
Cat.No: T10033
Synonym:
Target: COX
COX-2-IN-34
Cat.No: T77618
Synonym:
Target: COX
COX-2-IN-6
Cat.No: T62061
Synonym:
Target: COX, Prostaglandin Receptor
FK 3311
Cat.No: T7207
Synonym: N-[4-乙酰基-2-(2,4-二氟苯氧基)苯基]-甲烷磺酰胺,FK-3311,COX-2 Inhibitor V
Target: COX
Diclofenac diethylamine
Cat.No: T0432
Synonym:
Target: Apoptosis, COX
Indomethacin
Cat.No: T0458
Synonym: Indocin,Indometacine,吲哚美辛,Indomethacine,Indometacin
Target: Phospholipase, COX, PDE, Autophagy
Zaltoprofen
Cat.No: T6737
Synonym: CN100,扎托布洛芬,Soleton
Target: COX
(S)-(+)-Ibuprofen
Cat.No: T0448
Synonym: 左旋布洛芬,Dexibuprofen,(S)-Ibuprofen,(S)-(+)-布洛芬
Target: BCL, Thrombin, Cysteine Protease, COX, PPAR
Diclofenac Potassium
Cat.No: T6470
Synonym: 双氯芬酸钾,CGP-45840B,Cataflam,Voltfast
Target: Apoptosis, Others, COX
FPL 62064
Cat.No: T8356
Synonym:
Target: Lipoxygenase, COX
Diclofenac sodium
Cat.No: T1555
Synonym: GP 45840,双氯芬酸钠
Target: Apoptosis, COX
Diclofenac
Cat.No: T0196
Synonym: 双氯芬酸,奥尔芬,Diclofenacum,Voltaren
Target: Apoptosis, COX
Metyrosine
Cat.No: T22368
Synonym: 甲酪氨酸,α-Methyltyrosine
Target: COX
Losartan Carboxaldehyde
Cat.No: T7838
Synonym:
Target: COX
Firocoxib
Cat.No: T7596
Synonym: 非罗考昔,ML 1785713
Target: COX
Rebamipide
Cat.No: T1562
Synonym: Proamipide,OPC12759,瑞巴派特
Target: Free radical scavengers, COX, Prostaglandin Receptor
SC-58125
Cat.No: T23333
Synonym: SC 58125,1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑
Target: COX
NS-398
Cat.No: T3214
Synonym: N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide,NS398
Target: COX
Sertaconazole
Cat.No: T50005
Synonym:
Target: Antifungal
Dienogest
Cat.No: T2577
Synonym: 地诺孕素,STS 557
Target: Apoptosis, Estrogen/progestogen Receptor, Progesterone Receptor, Autophagy
TA-02
Cat.No: T4646
Synonym:
Target: p38 MAPK, Autophagy
COX-2-IN-30
Cat.No: T78705
Synonym:
Target: COX
COX-2-IN-26
Cat.No: T63480
Synonym:
Target:
COX-2-IN-9
Cat.No: T63646
Synonym:
Target:
COX-2-IN-31
Cat.No: T78706
Synonym:
Target: COX
COX-2-IN-11
Cat.No: T60457
Synonym:
Target:
COX-2-IN-18
Cat.No: T61760
Synonym:
Target:
COX-2-IN-7
Cat.No: T60978
Synonym:
Target:
COX-2-IN-32
Cat.No: T79130
Synonym:
Target: NF-κB
COX-2-IN-35
Cat.No: T79760
Synonym:
Target: COX
COX-2-IN-23
Cat.No: T63348
Synonym:
Target:
COX-2-IN-8
Cat.No: T62175
Synonym:
Target:
COX-2-IN-19
Cat.No: T61264
Synonym:
Target:
FR 122047
Cat.No: T22790
Synonym: 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride,1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride,FR 122047盐酸盐
Target: COX
COX-2-IN-16
Cat.No: T61821
Synonym:
Target:
COX-2-IN-13
Cat.No: T61714
Synonym:
Target:
COX-2-IN-22
Cat.No: T63215
Synonym:
Target:
Nitroaspirin
Cat.No: T16328
Synonym: 2-乙酰氧基苯甲酸-3-硝酸甲基苯酯,NCX 4016
Target: Apoptosis, COX
COX-2-IN-28
Cat.No: T64109
Synonym:
Target:
COX-2-IN-10
Cat.No: T63943
Synonym:
Target:
COX-2-IN-14
Cat.No: T61711
Synonym:
Target:
COX-2-IN-12
Cat.No: T60566
Synonym:
Target:
COX-2-IN-24
Cat.No: T64063
Synonym:
Target:
COX-2-IN-20
Cat.No: T60464
Synonym:
Target:
COX-2-IN-21
Cat.No: T62259
Synonym:
Target:
COX-2-IN-29
Cat.No: T63336
Synonym:
Target:
COX-2-IN-17
Cat.No: T62142
Synonym:
Target:
COX-2-IN-33
Cat.No: T78754
Synonym:
Target: COX
N-tert-butyl-α-Phenylnitrone
Cat.No: T23046
Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮
Target: ROS, COX
Cat. No. Product Name Target Signaling Pathways
T3824 Jaceosidin

Apoptosis; BCL; COX; UGT Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
Jaceosidin 是从毛莲蒿中得到的一种黄酮类天然产物,可激活Bax,下调 Mcl-1 和 c-FLIP 的表达,诱导癌细胞凋亡。它能够降低炎性因子水平,激活 NF-κB,抑制COX-2的表达,具有抗癌和抗炎作用。
T6S0413 Pectolinarigenin

柳穿鱼黄素,Pectolinaringenin

Others; Lipoxygenase; COX Immunology/Inflammation; Metabolism; Neuroscience; Others
Pectolinarigenin (Pectolinaringenin) 是 COX-2/5-LOX 的双重抑制剂,可抑制炎症病变中类花生酸的形成,具有抗炎活性。
T3399 Psoralidin

Others; Estrogen/progestogen Receptor; Reactive Oxygen Species; Lipoxygenase; Gamma-secretase; Akt; COX; Antibacterial Cytoskeletal Signaling; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Psoralidin 是COX-2和5-LOX 的抑制剂,有抗癌,抗菌和抗炎作用。它显著下调NOTCH1信号传导,还极大地诱导活化氧产生。
T5S0045 Isofraxidin

6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

MMP; ERK; p38 MAPK; TLR; COX Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分,抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞,抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达,还抑制TLR4/髓样分化蛋白 2 复合物的形成。
TN2139 Regaloside B

鸦胆子苦醇,王百合苷 B

NOS; COX; NO Synthase Immunology/Inflammation; Neuroscience
Regaloside B 是从麝香百合中分离出来的一种苯丙烷,可抑制iNOS 和COX-2的表达,具有抗炎活性。
T5758 sphondin

6-甲氧基当归素,牛防风素,牛防风素

COX; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Sphondin 具有抗惊厥、抗炎和抗增殖活性,对 IL-1beta 诱导的 A549 细胞中 COX-2 蛋白水平和 PGE(2) 释放的增加具有抑制作用。
T0649 Salicylic acid

2-Hydroxybenzoic acid,水杨酸

Apoptosis; Mitophagy; COX; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Neuroscience
Salicylic acid (2-Hydroxybenzoic acid) 是一种从柳树皮中提取的天然产物,是一种抗炎活性环加氧酶抑制剂,抑制COX-2活性。
T4643 TFAP

N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) 是环氧酶 1 的一种选择性抑制剂,IC50值为 0.8 μM。
T6S1572 Sauchinone

ERK; p38 MAPK; NF-κB MAPK; NF-κB
Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS,TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
T1301 Guaiacol

O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚

NF-κB; COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类,可抑制 LPS 刺激的COX-2表达和NF-κB 激活,具有抗炎活性。
TN3500 beta-Amyrone

β-Amyron,β-香树脂酮

COX; AChR; PPAR; Antifection DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
beta-Amyrone (β-Amyron) 对基孔肯雅病毒复制具有抗真菌活性,EC50 为 86 uM。 beta-Amyrone 通过抑制 COX-2 的表达而具有抗炎活性。 beta-Amyrone 表现出抗α-葡萄糖苷酶抑制活性和中等 AChE 活性。 β-Amyrone 可用于炎症、感染和肥胖等疾病的研究。
T0399 Methyl salicylate

Gaultheria oil,Methyl 2-hydroxybenzoate,2-Carbomethoxyphenol,Betula oil,水杨酸甲酯,Natural wintergreen oil,Wintergreen oil

COX; TRP/TRPV Channel Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
Methyl salicylate (Gaultheria oil) 是从番泻叶中提取的一种天然三萜皂苷,是一种局部缓解疼痛和抗炎作用的药物。 它还用作食品和烟草制品中的农药、变性剂、香料成分和调味剂。
T3779 Crocin II

Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B

Caspase; COX; NO Synthase Apoptosis; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
Crocin II (Crocetin gentiobiosylglucosyl ester) 是从栀子果实中分离出来的一种天然产物,具有抗氧化、抗癌和抗抑郁活性。它抑制 iNOS 和 COX-2的蛋白质和 m-RNA 的表达,还抑制NO 产生,IC50值为 31.1 μM。
T5S2360 Corydaline

Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline

P450; Virus Protease; Opioid Receptor; AChE Endocrinology/Hormones; GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Corydaline (Corydalin) 是从 Corydalis yanhusuo 提取的一种异喹啉生物碱,是一种新型促动力植物药的主要活性成分之一。它促进胃排空和小肠转运,促进胃的调节,具有抗乙酰胆碱酯酶、抗过敏和镇痛活性。
T0335 Sodium salicylate

水杨酸钠,Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt

Apoptosis; NF-κB; COX; S6 Kinase; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; MAPK; Neuroscience; NF-κB; PI3K/Akt/mTOR signaling
Sodium salicylate (2-Hydroxybenzoic acid sodium salt) 是一种S6K 的抑制剂,可抑制COX-2活性。它还是一种NF-κB 抑制剂,可降低炎症基因的表达,促进老化肌肉的修复。
T1633 β-Carotene

beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素

Apoptosis; ROS; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Metabolism
β-Carotene (Provitamin A) 是一种天然存在的视黄醇(维生素 A)前体。它是一种 ROS 调节剂,具有抗氧化和抗炎活性。它可作为抗氧化剂或者促氧化剂,可诱导乳腺癌细胞凋亡,具有抗癌活性。
T3883 Roburic acid

COX Immunology/Inflammation; Neuroscience
Roburic acid 是秦艽中的一种四环三萜类天然产物,作为COX 抑制剂,对 COX-1 和 COX-2 的IC50值分别为 5 和 9 μM。
T0065 Acetaminophen

对乙酰氨基酚,醋氨酚,4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol

COX; Endogenous Metabolite; Histone Acetyltransferase Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Neuroscience
Acetaminophen (APAP) 是一种 COX 抑制剂,抑制 COX-1 和 COX-2 (IC50=113.7/25.8 μM)。Acetaminophen 具有解热镇痛活性,以及较弱的抗炎活性。
T2826 Asaraldehyde

Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde,细辛醛

COX Immunology/Inflammation; Neuroscience
Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde) 是COX-2抑制剂,能够明显降低环加氧酶 II (COX-2) 的活性(IC50:100 μg/mL)。
TN1723 Hamaudol

COX Immunology/Inflammation; Neuroscience
Hamaudol 是从防风中分离出的一种色酮,有抗炎作用,可用于缓解疼痛的研究。它抑制环加氧酶COX-1和COX-2的活性,IC50值分别为 0.30 和 0.57 mM。
T2972 Rutaecarpine

Rutacarpine,吴茱萸次碱,Rhetine,Rutecarpine

COX Immunology/Inflammation; Neuroscience
Rutaecarpine (Rhetine) 是从槐木中提取的一种生物碱,是 COX-2的抑制剂,IC50值为0.28 μM。
T3868 Agnuside

牡荆油,穗花牡荆苷,chasteberry oil

COX; Prostaglandin Receptor; P-gp GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
Agnuside (chasteberry oil) 是从黄荆中分离得到的一种天然产物,可下调炎性介质PGE2和LTB4,减少细胞因子的表达,具有抗关节炎活性。
TN1377 α-Spinasterol

Α-波菜甾醇,alpha-Spinasterol,菠甾醇

COX; Antibacterial; TRP/TRPV Channel Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
α-Spinasterol 是一种从Spinacia oleracea 分离的瞬时受体电位香草酸 1 拮抗剂,具有抗菌、抗炎、抗抑郁、抗氧化和抗伤害作用。它抑制COX-1和COX-2活性,IC50值分别为 16.17 μM 和 7.76 μM。
T3747 syringaldehyde

Syringic aldehyde,丁香醛,Springaldehyde

COX Immunology/Inflammation; Neuroscience
syringaldehyde 是可从厚朴和木薯中分离得到的黄酮类多酚,具有抗氧化、抗高血糖和抗炎活性,可适度抑制COX-2活性,IC50为 3.5 μg/mL。
T6S0722 Isoorientin

Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素

Antioxidant; COX Immunology/Inflammation; Neuroscience; oxidation-reduction
Isoorientin (Homoorientin) 是一种 COX-2抑制剂,IC50值为 39 μM,具有抗氧化活性。
T2S1625 (E)-Ethyl p-methoxycinnamate

Ethyl para-methoxycinnamate,Ethyl 4-methoxycinnamate,4-Methoxycinnamic Acid Ethyl Ester,对甲氧基肉桂酸乙酯,Ethyl methoxycinnamate,Ethyl p-methoxycinnamate,EPMC

Others; COX Immunology/Inflammation; Neuroscience; Others
(E)-Ethyl p-methoxycinnamate (EPMC) 是从高良姜中提取的一种天然产物,具有抗炎、抗肿瘤和抗微生物作用。它在体外抑制COX-1和COX-2,IC50分别为 1.12 和 0.83 μM。
T4S0590 Columbin

Phospholipase; COX; Parasite Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
Columbin 是有口服活性的二萜呋喃内酯,选择性抑制COX-1和COX-2,EC50值为 327 μM 和 53.1 μM,具有抗炎和抗锥虫体作用。
TQ0288 Hexahydrocurcumin

Reactive Oxygen Species; ROS; COX Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Hexahydrocurcumin 是一种选择性口服活性COX-2抑制剂,对 COX-1 无活性,是姜黄素的主要代谢产物之一,。它具有抗氧化,抗癌和抗炎作用。
T3342 Xanthohumol

Apoptosis; Others; Influenza Virus; COX; Acyltransferase; HSV Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; Others
Xanthohumol 是从啤酒花中分离到的黄酮类化合物,可抑制 COX-1 和 COX-2 活性,具有抗肿瘤,抗血管生成的作用,还具有抗多种病毒的活性。
T3039 Hederagenin

Hederagenic acid,常春藤苷元,Astrantiagenin E,Caulosapogenin,常春藤皂苷元,Hederagenol

Others Others
Hederagenin (Hederagenol) 是一种三萜皂苷,可以抑制细胞中由于LPS 刺激引起的 iNOS、COX-2和 NF-κB 的表达。
T5430 [8]-Shogaol

8-SHOGAOL,8-姜烯酚

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
[8]-Shogaol 是生姜中的一种刺激性酚类天然产物,可诱导人白血病细胞凋亡,抑制 COX-2的IC50为17.5 μM,具有抗血小板活性,IC50为5 μM。
T1468 Lornoxicam

Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康

COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience
Lornoxicam (Chlortenoxicam) 是一种新型非甾体抗炎药,是高活性 COX-1 和 COX-2 抑制剂,IC50 分别为 5 和 8 nM。
T5759 S-(+)-Marmesin

(+)-Marmesin,异紫花前胡内酯,(S)-Marmesin,marmesin

Lipoxygenase; COX Immunology/Inflammation; Metabolism; Neuroscience
S-(+)-Marmesin (marmesin) 是一种从木橘成熟树皮中分离得到的香豆素,具有 COX-2/5-LOX 双重抑制活性。
TN1373 α-Humulene

Alpha-caryophyllene,ALPHA-律草烯

TNF; NOS; COX Apoptosis; Immunology/Inflammation; Neuroscience
α-Humulene (Alpha-caryophyllene) 是 Tanacetum vulgareL. 精油的主要成分,显示出抗炎作用,IC50=15±2 μg/mL。它抑制 iNOS 和COX-2表达。
TN7025 Canolol

菜籽多酚,Phenol, 4-ethenyl-2,6-dimethoxy-

COX Immunology/Inflammation; Neuroscience
Canolol (Phenol, 4-ethenyl-2,6-dimethoxy-) 是一种抗氧化酚类化合物,可用作 COX-2 抑制剂。
T3811 Ginsenoside C-K

20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K

P450; cell cycle arrest; COX; NO Synthase Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
Ginsenoside C-K (Ginsenoside K) 是 Ginsenoside Rb1 的细菌代谢物,可通过抑制诱生型一氧化氮合酶和COX-2来发挥抗炎作用。它在人肝微粒体中抑制CYP2C9和CYP2A6活性,IC50分别为 32.0±3.6 和 63.6±4.2 μM。
TC0036 Compound Lup-20(29)-en-3-yl acetate

IL Receptor; VEGFR; Others; TNF; COX Angiogenesis; Apoptosis; Immunology/Inflammation; Neuroscience; Others; Tyrosine Kinase/Adaptors
Lup-20(29)-en-3-yl acetate 是 Lupeol 的衍生物,通过下调 TNF-α、IL-1β、MCP-1、COX-2、VEGF 和颗粒酶 B 来抑制类风湿性关节炎的进展。
T3918 Ginsenoside Rb3

人参皂苷 Rb3,Gypenoside IV,人参皂苷Rb3

NF-κB; COX; NO Synthase Immunology/Inflammation; Neuroscience; NF-κB
Ginsenoside Rb3 (Gypenoside IV) 是从三七中提取的一种天然产物。它在 293T 细胞系中抑制 TNFα 诱导的NF-κB 转录活性,IC50为 8.2 μM。它还抑制COX-2和iNOSmRNA 的诱导。
T4S2126 Ginkgetin

银杏双黄酮,银杏素

Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
Ginkgetin 是从银杏叶中分离得到的一种双黄酮,具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂,IC50值为 5.92 μM。
T6S0077 Byakangelicol

COX Immunology/Inflammation; Neuroscience
Byakangelicol 是一种分离自白芷的白三醇,能够抑制环加氧酶-2的表达及活性,从而减少白细胞介素-1β诱导的 A549 细胞中前列腺素 E2 的释放。它可用于研究气道炎症。
T6S1543 Dehydrodiisoeugenol

去氢二异丁香酚,脱氢二异丁香酚

Others; NF-κB; COX; Antibacterial Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB; Others
Dehydrodiisoeugenol 是从Myristica fragrans Houtt 中分离得到的天然产物,具有抗炎和抗菌作用。它抑制 LPS 刺激的小鼠巨噬细胞中NF-κB 活化和环氧合酶 (COX)-2 基因的表达。
T5431 [10]-Shogaol

10-姜烯酚,10-Shogaol

Antioxidant; COX Immunology/Inflammation; Neuroscience; oxidation-reduction
[10]-Shogaol (10-Shogaol) 是一种从生姜中提取的抗氧化剂,用于皮肤细胞增殖和迁移增强剂。它抑制 COX-2,IC50值为 7.5 μM,可能有降血脂和胰岛素增敏作用。
T25253 Cinnamtannin B-1

Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358,肉桂单宁B-1

Antioxidant; COX Immunology/Inflammation; Neuroscience; oxidation-reduction
Cinnamtannin B-1 (LDN 0022358) 是一种 A 型原花青素,包含在多种植物中,如越桔、桂树、泽兰肉桂和猪苓。它是一种有效的抗氧化剂和保护剂,可对抗人类血小板的氧化应激和凋亡。它是一种 Cox-2抑制剂。
T4A2456 Gamabufotalin

Gamabufagin,日本蟾蜍毒苷元

COX Immunology/Inflammation; Neuroscience
Gamabufotalin (Gamabufagin) 是一种蟾蜍甾烯,存在于蟾酥中。它稳定性高,毒性低,被广泛用于癌症的研究。
T4S1616 Sanggenon D

桑根酮D,Sanggenone D

NOS; COX; GABA Receptor Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
Sanggenone D represents a new scaffold of positive GABAA receptor modulators, it also inhibits COX-2 activity (IC 50 = 73-100 μM). Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 ce
TQ0180 Chebulagic acid

SARS-CoV; Influenza Virus; Lipoxygenase; COX Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的一种 COX-LOX 双重抑制剂,有抗炎和抗感染作用。它抑制 SARS-CoV-2病毒的复制,EC50值为 9.76 μM。它还是 M2(S31N)抑制剂和抗流感病毒剂。
T6S2023 Harpagoside

Others; COX; NO Synthase Immunology/Inflammation; Neuroscience; Others
Harpagoside 是从爪钩草中分离出来的一种天然产物,可抑制COX-1和COX-2活性,并抑制 NO 的产生。
T5714 5-O-Demethylnobiletin

5-DEMETHYLNOBILETIN,去甲基川陈皮素

Leukotriene Receptor; Lipoxygenase GPCR/G Protein; Metabolism
5-O-Demethylnobiletin (5-DEMETHYLNOBILETIN) 是从黄芪中分离出的多甲氧基黄酮,具有抗炎活性,可通过直接抑制 5-LOX 发挥作用,IC50为 0.1 μM。
T5S1981 alpha-Cyperone

(+)-α-Cyperone,α-香附酮,α-Cyperone

Others; Endogenous Metabolite Metabolism; Others
alpha-Cyperone (α-Cyperone) 与 IL-6, Cox-2, Cdc42, Nck-2, Rac1 的表达下调相关,从而能够抑制炎症反应。
T5727 CAFESTOL

咖啡醇,咖啡油醇

ERK; NF-κB; COX; PGE Synthase Immunology/Inflammation; MAPK; Neuroscience; NF-κB
Cafestol 是咖啡特有的一种二萜,可靶向 AP-1 抑制ERK,有化学预防、抗肿瘤、保肝、抗氧化和抗炎作用。它通过抑制NF-kB 活化途径强烈的抑制 PGE2的产生,还抑制 LGE 激活的 RAW264.7 细胞中的PGE2产生和环氧合酶(COX-2)的 mRNA 表达。
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天然产物

Jaceosidin
Cat.No: T3824
Synonym:
Target: Apoptosis, BCL, COX, UGT
Pectolinarigenin
Cat.No: T6S0413
Synonym: 柳穿鱼黄素,Pectolinaringenin
Target: Others, Lipoxygenase, COX
Psoralidin
Cat.No: T3399
Synonym:
Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial
Isofraxidin
Cat.No: T5S0045
Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶
Target: MMP, ERK, p38 MAPK, TLR, COX
Regaloside B
Cat.No: TN2139
Synonym: 鸦胆子苦醇,王百合苷 B
Target: NOS, COX, NO Synthase
sphondin
Cat.No: T5758
Synonym: 6-甲氧基当归素,牛防风素,牛防风素
Target: COX, Prostaglandin Receptor
Salicylic acid
Cat.No: T0649
Synonym: 2-Hydroxybenzoic acid,水杨酸
Target: Apoptosis, Mitophagy, COX, Endogenous Metabolite, Autophagy
TFAP
Cat.No: T4643
Synonym: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
Target: COX, Endogenous Metabolite
Sauchinone
Cat.No: T6S1572
Synonym:
Target: ERK, p38 MAPK, NF-κB
Guaiacol
Cat.No: T1301
Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚
Target: NF-κB, COX, Endogenous Metabolite
beta-Amyrone
Cat.No: TN3500
Synonym: β-Amyron,β-香树脂酮
Target: COX, AChR, PPAR, Antifection
Methyl salicylate
Cat.No: T0399
Synonym: Gaultheria oil,Methyl 2-hydroxybenzoate,2-Carbomethoxyphenol,Betula oil,水杨酸甲酯,Natural wintergreen oil,Wintergreen oil
Target: COX, TRP/TRPV Channel
Crocin II
Cat.No: T3779
Synonym: Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B
Target: Caspase, COX, NO Synthase
Corydaline
Cat.No: T5S2360
Synonym: Corydalin,紫堇碱,延胡索甲素,(+)-Corydaline
Target: P450, Virus Protease, Opioid Receptor, AChE
Sodium salicylate
Cat.No: T0335
Synonym: 水杨酸钠,Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt
Target: Apoptosis, NF-κB, COX, S6 Kinase, Autophagy
β-Carotene
Cat.No: T1633
Synonym: beta-胡萝卜素,Carotaben,Beta-Carotene,Provitamin A,β-胡萝卜素
Target: Apoptosis, ROS, Endogenous Metabolite
Roburic acid
Cat.No: T3883
Synonym:
Target: COX
Acetaminophen
Cat.No: T0065
Synonym: 对乙酰氨基酚,醋氨酚,4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol
Target: COX, Endogenous Metabolite, Histone Acetyltransferase
Asaraldehyde
Cat.No: T2826
Synonym: Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde,细辛醛
Target: COX
Hamaudol
Cat.No: TN1723
Synonym:
Target: COX
Rutaecarpine
Cat.No: T2972
Synonym: Rutacarpine,吴茱萸次碱,Rhetine,Rutecarpine
Target: COX
Agnuside
Cat.No: T3868
Synonym: 牡荆油,穗花牡荆苷,chasteberry oil
Target: COX, Prostaglandin Receptor, P-gp
α-Spinasterol
Cat.No: TN1377
Synonym: Α-波菜甾醇,alpha-Spinasterol,菠甾醇
Target: COX, Antibacterial, TRP/TRPV Channel
syringaldehyde
Cat.No: T3747
Synonym: Syringic aldehyde,丁香醛,Springaldehyde
Target: COX
Isoorientin
Cat.No: T6S0722
Synonym: Homoorientin,Luteolin-6-C-glucoside,异荭草苷;异荭草素,异荭草素
Target: Antioxidant, COX
(E)-Ethyl p-methoxycinnamate
Cat.No: T2S1625
Synonym: Ethyl para-methoxycinnamate,Ethyl 4-methoxycinnamate,4-Methoxycinnamic Acid Ethyl Ester,对甲氧基肉桂酸乙酯,Ethyl methoxycinnamate,Ethyl p-methoxycinnamate,EPMC
Target: Others, COX
Columbin
Cat.No: T4S0590
Synonym:
Target: Phospholipase, COX, Parasite
Hexahydrocurcumin
Cat.No: TQ0288
Synonym:
Target: Reactive Oxygen Species, ROS, COX
Xanthohumol
Cat.No: T3342
Synonym:
Target: Apoptosis, Others, Influenza Virus, COX, Acyltransferase, HSV
Hederagenin
Cat.No: T3039
Synonym: Hederagenic acid,常春藤苷元,Astrantiagenin E,Caulosapogenin,常春藤皂苷元,Hederagenol
Target: Others
[8]-Shogaol
Cat.No: T5430
Synonym: 8-SHOGAOL,8-姜烯酚
Target: Apoptosis, COX
Lornoxicam
Cat.No: T1468
Synonym: Ro 13-9297,Chlortenoxicam,TS110,氯诺昔康
Target: COX, Endogenous Metabolite
S-(+)-Marmesin
Cat.No: T5759
Synonym: (+)-Marmesin,异紫花前胡内酯,(S)-Marmesin,marmesin
Target: Lipoxygenase, COX
α-Humulene
Cat.No: TN1373
Synonym: Alpha-caryophyllene,ALPHA-律草烯
Target: TNF, NOS, COX
Canolol
Cat.No: TN7025
Synonym: 菜籽多酚,Phenol, 4-ethenyl-2,6-dimethoxy-
Target: COX
Ginsenoside C-K
Cat.No: T3811
Synonym: 20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K
Target: P450, cell cycle arrest, COX, NO Synthase
Compound Lup-20(29)-en-3-yl acetate
Cat.No: TC0036
Synonym:
Target: IL Receptor, VEGFR, Others, TNF, COX
Ginsenoside Rb3
Cat.No: T3918
Synonym: 人参皂苷 Rb3,Gypenoside IV,人参皂苷Rb3
Target: NF-κB, COX, NO Synthase
Ginkgetin
Cat.No: T4S2126
Synonym: 银杏双黄酮,银杏素
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Byakangelicol
Cat.No: T6S0077
Synonym:
Target: COX
Dehydrodiisoeugenol
Cat.No: T6S1543
Synonym: 去氢二异丁香酚,脱氢二异丁香酚
Target: Others, NF-κB, COX, Antibacterial
[10]-Shogaol
Cat.No: T5431
Synonym: 10-姜烯酚,10-Shogaol
Target: Antioxidant, COX
Cinnamtannin B-1
Cat.No: T25253
Synonym: Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358,肉桂单宁B-1
Target: Antioxidant, COX
Gamabufotalin
Cat.No: T4A2456
Synonym: Gamabufagin,日本蟾蜍毒苷元
Target: COX
Sanggenon D
Cat.No: T4S1616
Synonym: 桑根酮D,Sanggenone D
Target: NOS, COX, GABA Receptor
Chebulagic acid
Cat.No: TQ0180
Synonym:
Target: SARS-CoV, Influenza Virus, Lipoxygenase, COX
Harpagoside
Cat.No: T6S2023
Synonym:
Target: Others, COX, NO Synthase
5-O-Demethylnobiletin
Cat.No: T5714
Synonym: 5-DEMETHYLNOBILETIN,去甲基川陈皮素
Target: Leukotriene Receptor, Lipoxygenase
alpha-Cyperone
Cat.No: T5S1981
Synonym: (+)-α-Cyperone,α-香附酮,α-Cyperone
Target: Others, Endogenous Metabolite
CAFESTOL
Cat.No: T5727
Synonym: 咖啡醇,咖啡油醇
Target: ERK, NF-κB, COX, PGE Synthase
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Cat. No. Product Name Species Expression System
TMPY-01736 COX-2 Protein, Human, Recombinant (His)

GRIPGHS,PHS-2,hCox-2,COX...

Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ...
TMPJ-00704 SCO1 Protein, Human, Recombinant (GST)

Protein SCO1 Homolog Mitochondrial,SCOD1,SCO1

Human E. coli
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4...
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Protein T1,suppression of tumorigenicity 2,Ly84,DER...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02011 CD96 Protein, Human, Recombinant (His)

CD96 molecule,TACTILE

Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His)

A630052E07Rik,OSF-2,Osf2,PLF,AI74...

Mouse HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-02096 TACI Protein, Human, Recombinant (His)

RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...

Human HEK293 Cells
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His)

KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...

Human E. coli
KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His)

SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...

Human HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-04844 BTN3A1 Protein, Human, Recombinant (His)

BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...

Human HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-05288 PLGF/PGF Protein, Human, Recombinant (aa 19-149)

PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...

Human E. coli
PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-02820 SDF-1 Protein, Human, Recombinant (isoform a)

SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1

Human E. coli
SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Gp39,AW208766,Brp39,chitinase 3 like 1

Mouse HEK293 Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST)

v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...

Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01985 CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

FCGR2,FCGR21,CD32A,FCG2,...

Human HEK293 Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04644 PDGFB Protein, Human, Recombinant (His)

platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...

Human P. pastoris (Yeast)
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-05414 NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

D6H12S2489E,NKG2-D,killer cell le...

Mouse Baculovirus Insect Cells
NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...

Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293)

HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...

Human HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His)

KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...

Human E. coli
KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-01359 ST2/IL-1 RL1 Protein, Human, Recombinant (His)

IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00747 Nectin-2 Protein, Human, Recombinant (His)

PVRR2,Nectin-2,poliovirus receptor-related...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-05427 CD19 Protein, Human, Recombinant (hFc)

CVID3,B4,CD19 molecule

Human HEK293 Cells
CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335 TGFBR2 Protein, Mouse, Recombinant (His)

TGFR-2,TGF-beta type II receptor,Transforming growt...

Mouse HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-04051 c-Kit Protein, Human, Recombinant (hFc)

SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-00005 FGF-8a Protein, Human, Recombinant

fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425 Tau Protein, Human, Recombinant (His)

PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...

Human E. coli
MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-01199 CD74 Protein, Human, Recombinant (His)

II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompatibility co...

Human HEK293 Cells
CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-05586 CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMIGD2,IGPR-1,transmembrane and immunoglobulin doma...

Human HEK293 Cells
The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu...
TMPY-00849 ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc)

HML2,CD301,CLECSF13,HML,MGL,C-type lectin domain fa...

Human HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPY-02432 VEGF164 Protein, Rat, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Rat Baculovirus Insect Cells
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-02231 TrkB Protein, Mouse, Recombinant (His)

trk-B,neurotrophic tyrosine kinase, receptor, type 2

Mouse HEK293 Cells
TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-02367 Neuropilin-1 Protein, Human, Recombinant (isoform b, His)

neuropilin 1,NRP,VEGF165R,BDCA4,Neuropilin-1,NP1,CD304

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
TMPY-00748 Nectin-2 Protein, Human, Recombinant

PRR2,Nectin-2,PVRR2,poliovirus re...

Human HEK293 Cells
Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-04829 G-CSF Protein, Human, Recombinant

G-CSF,colony stimulating factor 3 (granulocyte),集落刺激因子,CSF3O...

Human HEK293 Cells
G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-00850 ST2/IL-1 RL1 Protein, Human, Recombinant

ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2...

Human HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02358 CD98 Protein, Mouse, Recombinant (His)

NACAE,AI314110,Ly-m10,Cd98,Mgp-2hc,4F2HC,L...

Mouse HEK293 Cells
CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
TMPY-00871 LAYN Protein, Human, Recombinant (hFc)

layilin

Human HEK293 Cells
LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-00392 PAM Protein, Human, Recombinant (His)

PAL,peptidylglycine alpha-amidating monooxygenase,peptidylgl...

Human HEK293 Cells
PAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 94.4 kDa and the accession number is P19021-2.
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His)

NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2

Human E. coli
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His)

HAGH1,GLO2,GLX2,hydroxyacylglutathione hyd...

Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. HAGH belongs to the Metallo-beta-lactamase superfamily. HAGH is widely expressed in the kidney, liver, and other tissues. Diseases associated with HAGH include Hydroxyacyl Glutathio...
TMPY-04999 GAS6 Protein, Human, Recombinant (His)

Human HEK293
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ...
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重组蛋白

COX-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01736
Species: Human
Expression System: Baculovirus Insect Cells
SCO1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-00704
Species: Human
Expression System: E. coli
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Cat.No: TMPJ-00850
Species: Mouse
Expression System: HEK293 Cells
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Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
CD96 Protein, Human, Recombinant (His)
Cat.No: TMPY-02011
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01613
Species: Mouse
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
TACI Protein, Human, Recombinant (His)
Cat.No: TMPY-02096
Species: Human
Expression System: HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
Cat.No: TMPY-00341
Species: Human
Expression System: HEK293 Cells
KRAS Protein, Human, Recombinant (G12D, His)
Cat.No: TMPY-06056
Species: Human
Expression System: E. coli
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His)
Cat.No: TMPY-01691
Species: Human
Expression System: HEK293 Cells
BTN3A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04844
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (aa 19-149)
Cat.No: TMPY-05288
Species: Human
Expression System: E. coli
SDF-1 Protein, Human, Recombinant (isoform a)
Cat.No: TMPY-02820
Species: Human
Expression System: E. coli
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293 Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02500
Species: Mouse
Expression System: HEK293 Cells
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Cat.No: TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-01985
Species: Human
Expression System: HEK293 Cells
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Cat.No: TMPY-04644
Species: Human
Expression System: P. pastoris (Yeast)
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Cat.No: TMPY-05414
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
Cat.No: TMPY-01871
Species: Human
Expression System: HEK293 Cells
GDNF Protein, Human, Recombinant (HEK293)
Cat.No: TMPY-02792
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human, Recombinant (Q61H, His)
Cat.No: TMPY-01888
Species: Human
Expression System: E. coli
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01359
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00747
Species: Human
Expression System: HEK293 Cells
CD19 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05427
Species: Human
Expression System: HEK293 Cells
TGFBR2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00335
Species: Mouse
Expression System: HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04051
Species: Human
Expression System: HEK293 Cells
FGF-8a Protein, Human, Recombinant
Cat.No: TMPY-00005
Species: Human
Expression System: E. coli
Tau Protein, Human, Recombinant (His)
Cat.No: TMPY-03425
Species: Human
Expression System: E. coli
CD74 Protein, Human, Recombinant (His)
Cat.No: TMPY-01199
Species: Human
Expression System: HEK293 Cells
CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05586
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00849
Species: Human
Expression System: HEK293 Cells
CLEC10A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02971
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Rat, Recombinant
Cat.No: TMPY-02432
Species: Rat
Expression System: Baculovirus Insect Cells
TrkB Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02231
Species: Mouse
Expression System: HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (isoform b, His)
Cat.No: TMPY-02367
Species: Human
Expression System: HEK293 Cells
Nectin-2 Protein, Human, Recombinant
Cat.No: TMPY-00748
Species: Human
Expression System: HEK293 Cells
G-CSF Protein, Human, Recombinant
Cat.No: TMPY-04829
Species: Human
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Human, Recombinant
Cat.No: TMPY-00850
Species: Human
Expression System: HEK293 Cells
CD98 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02358
Species: Mouse
Expression System: HEK293 Cells
LAYN Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00871
Species: Human
Expression System: HEK293 Cells
PAM Protein, Human, Recombinant (His)
Cat.No: TMPY-00392
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
Cat.No: TMPY-04116
Species: Human
Expression System: E. coli
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
Cat.No: TMPY-02288
Species: Human
Expression System: E. coli
GAS6 Protein, Human, Recombinant (His)
Cat.No: TMPY-04999
Species: Human
Expression System: HEK293
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